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AUTOIMMUNITY
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IMMUNOASSAY PERFORMANCE
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ASSAY
DESIGNAntibody Quality
Purity of Antigen
Buffer Formulation
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SYSTEM
DESIGNIncubation Times
Flexible Protocols
Temperature Control
Metering Accuracy
Reliability
Wash Performance
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MEASURING
TECHNOLOGYDirect Chemiluminescence
Acridinum Label
Sensitivity
Precision
CHEMILUMINESCENCE PRINCIPLE(CLIA)
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Magnetic Beads / Homogeneous Immunoassay
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Biotin-Avidin System
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Acridinium Ester Substrate
Increased Sensitivity
• Greatly increased solid phase surface area
Excellent Reproducibility
• Easier Ag/Ab labelling
• Biotin-avidin high affinity constant (106 higher than Ag-Ab)
Superior IA Performance
• Direct chemiluminescence
• Very low background
• Easier Ag/Ab labelling/ Good stability
• Small molecule of AE, not interfere Ag/Ab activity
